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According to the literature, the history of vaccination can be traced back to as early as the 7th century when the monks in India tried to immunize themselves by drinking snake . The first vaccination was inoculation with human smallpox, a practice widely carried out in ancient India, Arabia, and China. This method of vaccination consisted of collecting pus from a patient suffering from form of smallpox virus infection and the sample to a healthy human, which later led to a minor infection.
This method was first introduced in England by a Greek named E. Timoni. However, this method had a risk of spreading smallpox in the community and even worsening the health condition of the person who received the inoculation.
While the use of human smallpox vaccine was , E. Jenner came up with bovine smallpox vaccine in 1796; this new method also faced controversy, but continued to be . Smallpox became a preventable disease by injecting pus extracted from a human infected with cowpox virus. Jenner named the substance "vaccine" after the Latin word "vacca" which means "cow," and thus the process of giving vaccine became "vaccination".