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Drug resistance
d) The connection of the amino acid leucine to drug resistance raises hopes that a relatively simple intervention, like a shift to a low-leucine diet, can reduce the incidence of drug resistance, which is responsible for a large portion of the roughly 40,000 breast cancer deaths every year.
c) The work also raises the possibility that a drug could be developed to mirror the effects of that dietary restriction, by blocking cells’ ability to take in leucine from the surrounding environment.
b) Now, researchers have identified an ordinary dietary element that may increase the chances of a breast cancer becoming drug-resistant.
a) Drug resistance is the leading cause of death in women with estrogen-receptor-positive breast cancer, the most common form of the disease.